Pictures of lamotrigine rash

Lamictal rash is a side effect of the anti-seizure drug Lamictal, which contains a medication known as lamotrigine. The rash ranges from a mild annoyance to a possibly life threatening complication.

Some people develop a rash while taking it. A review of existing studies found that 10 percent of people in controlled trials had a reaction to Lamictal, which put them at risk of developing a rash. While rashes caused by Lamictal are often harmless, they can sometimes be life-threatening. The FDA placed a black box warning on the Lamictal label to warn people about this risk. Make sure you know the signs of a serious rash caused by Lamictal so you can get treatment quickly if it does occur. The symptoms of a mild rash caused by Lamictal are:. While a rash with these symptoms is likely not dangerous, still tell your doctor so they can monitor you for any other side effects.

Pictures of lamotrigine rash

Federal government websites often end in. The site is secure. A year-old boy with epilepsy presented with a maculopapular rash over the face fig 1. He had been started on lamotrigine 4 weeks earlier. The rash spread and he developed itching. Lamotrigine was stopped and treatment started with antihistamines and steroids. Of all the adverse events associated with lamotrigine, rash has caused the greatest concern and been the most frequent reason for stopping lamotrigine. Rash usually occurs within 12 weeks of initiation of treatment. The risk factors include the concomitant use of valproate and exceeding the recommended starting dose or rate of dose escalation. It is difficult to predict the progression of the rash and to establish the cause. If there is no alternate explanation, it must be presumed to be due to lamotrigine; the drug should be stopped immediately and the neurologist involved in the care should be contacted to discuss how to handle the potential worsening of seizures. This article has been adapted from one previously published in EMJ ; As a library, NLM provides access to scientific literature.

We did stop taking the lamictal and are waiting on our neuro to call back and tell us what to do. Open in a separate window.

Background: Lamotrigine may cause severe skin reactions. There is a known interaction between lamotrigine and valproic acid with an increase in lamotrigine levels and lamotrigine toxicity risk. Few cases of severe rash and systemic reactions in bipolar patients using lamotrigine and valproate have been reported. Case presentation: An year-old female adolescent with bipolar disorder type I was treated with lamotrigine, magnesium valproate, and perospirone for 12 days. After the last dose of lamotrigine, she abruptly developed generalized rash and swollen lymph nodes, which continued to progress over the next 3 days.

Treatment starts with discontinuing medications. Lamictal lamotrigine is an antiepileptic medication that works to prevent seizures but also has other uses. Sometimes this is a mild skin reaction that resolves, but it could be a sign of a serious and potentially fatal physical response to the medication. Lamictal rash can be treated, but you need to get medical attention right away if you start to have any signs of a rash while taking Lamictal—even if the symptoms are mild. This article explains how you can recognize a Lamictal rash and what you should do if you start to develop any type of skin reaction or allergic response during or after Lamictal use. A Lamictal rash can begin anywhere on your skin. Sometimes this rash is localized on just one area of the body, or it can be generalized, affecting the face, hands, arms, feet, neck, trunk, and back. The rash can appear as small, clustered, pinkish bumps, and it can feel itchy or slightly sore. In severe cases, blisters or peeling of the skin may develop—sometimes within just a few hours of the first signs of a rash. Symptoms that may accompany a Lamictal rash include:.

Pictures of lamotrigine rash

Daniel B. Block, MD, is an award-winning, board-certified psychiatrist who operates a private practice in Pennsylvania. Lamictal lamotrigine is an anticonvulsive drug frequently used as a mood stabilizer for people living with bipolar disorder. It works by moderating extreme variations in mood and is particularly helpful in treating severe depression. The medication has enjoyed widespread use since its introduction in Despite its proven benefits, Lamictal has its downsides. In some individuals, Lamictal has been known to cause a hypersensitivity reaction marked by severe rash and inflammation.

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List of Partners vendors. In addition, forum questions and responses include information and content that has been generated by epilepsy community members. A review of existing studies found that 10 percent of people in controlled trials had a reaction to Lamictal, which put them at risk of developing a rash. How we reviewed this article: Sources. The risk of getting a serious rash from Lamictal is low. Rash during lamotrigine treatment is not always drug hypersensitivity: A retrospective cohort study among children and adults. Bommersbach, T. What are the symptoms of a rash from Lamictal? Cardones, A. Symptoms of a more serious rash can include peeling skin, painful blisters, inflammation of the eyes, swollen lymph nodes, and flu-like symptoms.

Some people develop a rash while taking it.

More Skin Conditions. Miyagawa, F. We have selected the best…. Medically reviewed by Aleah Rodriguez, PharmD. A possible explanation for this is that the half-life of lamotrigine in healthy adults is 24—35 h, which may increase to nearly 70 h when combined with valproate. When you start taking Lamictal, make sure you understand exactly how much to take and when to take it. It may be due to the discontinuation of lamotrigine prior to the occurrence of rash. What are simple partial seizures? May, T. The information on these pages should not be substituted for medical advice from a healthcare provider. Use profiles to select personalised advertising. Read this next.