Thuoc prednisone 20 mg
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Prednisone is a glucocorticoid. Glucocorticoids are adrenocortical steroids, both naturally occurring and synthetic, which are readily absorbed from the gastrointestinal tract. Prednisone is a white to practically white, odorless, crystalline powder. It is very slightly soluble in water; slightly soluble in alcohol, in chloroform, in dioxane, and in methanol. The chemical name for prednisone is pregna-1, 4-diene-3, 11, trione, 17, dihydroxy-. Prednisone Tablets, USP are available in three strengths: 5 mg, 10 mg, and 20 mg.
Thuoc prednisone 20 mg
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Product Information. A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy.
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Prednisone provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation swelling , severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, endocrine problems, eye or vision problems, stomach or bowel problems, lupus, skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis. Prednisone is a corticosteroid cortisone-like medicine or steroid. It works on the immune system to help relieve swelling, redness, itching, and allergic reactions. There is a problem with information submitted for this request.
Thuoc prednisone 20 mg
If you have a condition involving inflammation swelling in your body, your doctor may prescribe prednisone. Examples of these conditions include:. Prednisone belongs to a group of drugs called corticosteroids often referred to as steroids. Prednisone comes as an immediate-release tablet that you swallow. An immediate-release drug is released into your body right away. Prednisone also comes in other forms taken by mouth, but these are not covered in this article.
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Psychic derangements may appear when corticosteroids are used, ranging from euphoria, insomnia, mood swings, personality changes, and severe depression, to frank psychotic manifestations. Similar articles in PubMed. The initial dosage should be maintained or adjusted until a satisfactory response is noted. Patients should also be advised that if they are exposed, medical advice should be sought without delay. Prednisone is a white to practically white, odorless, crystalline powder. The use of Prednisone Tablets, USP in active tuberculosis should be restricted to those cases of fulminating or disseminated tuberculosis in which the corticosteroid is used for the management of the disease in conjunction with an appropriate anti-tuberculous regimen. Prednisone is a prodrug to prednisolone, which mediates its glucocorticoid effects. Acting primarily through the hypothalamus a fall in free cortisol stimulates the pituitary gland to produce increasing amounts of corticotropin ACTH while a rise in free cortisol inhibits ACTH secretion. Convulsions have been reported with concurrent use of methylprednisolone and cyclosporine. Naturally occurring glucocorticoids hydrocortisone and cortisone , which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Complete control of symptoms will not be possible in all patients. After cell surface receptor attachment and entry into the cell, prednisone enters the nucleus, binds, and activates specific nuclear receptors, resulting in altered gene expression and inhibition of proinflammatory cytokine production.
Prednisone provides relief for inflamed areas of the body. It is used to treat a number of different conditions, such as inflammation swelling , severe allergies, adrenal problems, arthritis, asthma, blood or bone marrow problems, endocrine problems, eye or vision problems, stomach or bowel problems, lupus, skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis.
Significant cardiovascular and metabolic effects are hypertension, hyperglycemia, and dyslipidemia. After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached. Follow NCBI. After cell surface receptor attachment and entry into the cell, prednisone enters the nucleus, binds, and activates specific nuclear receptors, resulting in altered gene expression and inhibition of proinflammatory cytokine production. While on corticosteroid therapy patients should not be vaccinated against smallpox. The lowest possible dose of corticosteroid should be used to control the condition under treatment, and when reduction in dosage is possible, the reduction should be gradual. The purpose of this mode of therapy is to provide the patient requiring long-term pharmacologic dose treatment with the beneficial effects of corticoids while minimizing certain undesirable effects, including pituitary-adrenal suppression, the Cushingoid state, corticoid withdrawal symptoms, and growth suppression in children. These effects are less likely to occur with the synthetic derivatives except when used in large doses. Although controlled clinical trials have shown corticosteroids to be effective in speeding the resolution of acute exacerbations of multiple sclerosis, they do not show that corticosteroids affect the ultimate outcome or natural history of the disease. Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa such as:. Some of these preventative measures include using lower potency dosages and starting patients on the lowest effective dosage per guidelines. A steroid treatment card can be recommended to show to all healthcare professionals involved in their care and management. Persons who are on drugs which suppress the immune system are more susceptible to infections than healthy individuals. Contraindications to the administration of prednisone include the presence of systemic fungal infections. Recovery time for normal HPA activity is variable depending upon the dose and duration of treatment.
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