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Phospholipase D PLD is a potential therapeutic target against cancer, 이혜성. However, the contribution of PLD inhibition to the antitumor response remains unknown. We developed a potent and selective PLD1 inhibitor based on computer-aided drug design. The inhibitor enhanced apoptosis 이혜성 colorectal cancer CRC 이혜성 but not in normal colonic cells, and in vitro cardiotoxicity was not observed, 이혜성.

Lau 4,5,6,7 , Kenneth K. Leung 4 , Adrienne Y. Chan 4,5,6,10 , Celine S. Chui 6,11,12 , Ian C. Wong 4,5,6,7,13 , Ju-Young Shin 1,2, Background Polypharmacy among older people represents a global challenge due to its association with adverse drug events.

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Lee was in a relationship with Jun Hyun-moo , a former announcer turned broadcast personality and host. This biographical article about a South Korean personality is a stub. You can help Wikipedia by expanding it. This Asian biographical article related to television is a stub. Contents move to sidebar hide. Article Talk. Read Edit View history. Tools Tools.

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Tuesday 13 February Related Tags Add tags. Friday 1 December Wednesday 13 December Moreover, PLD1 inhibition attenuated colitis-associated CRC and orthotopically injected tumors, probably by controlling multiple pathways, including Wnt signaling, phagocytosis checkpoints, and immune signaling. Friday 29 December Tuesday 21 November Thursday 7 December Tuesday 24 October Saturday 30 December

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Monday 18 December Thursday 22 February Saturday 11 November Wednesday 22 November Saturday 20 January Monday 20 November The inhibitor enhanced apoptosis in colorectal cancer CRC cells but not in normal colonic cells, and in vitro cardiotoxicity was not observed. Thursday 1 February The reported prevalence of polypharmacy varies widely across countries, and is particularly high in Asian countries. Sunday 7 January